I’ve sat with 5MeO-DMT over a dozen times, always in the form of Bufo flake from the toad. It has been one of the most transformational and healing modality I’ve encountered. I have a low dose Jaguar (synthetic) pen that I use occasionally.

I’ve also used NN from a pen. It gave me a strange body load and intense kaleidoscopic visuals.

I did a LOT of that. We made our own in undergrad; depending on audacity and effort we made stuff ranging from beautifully clear, crystalline needles to stuff that looked like satans' earwax. Extremely memorable stuff, that at that moment in life, was a very good thing to happen to me in order to learn how to connect with my feelings.

I did it once. Felt like my consciousness rocketed "up" out of my body, but not up through physical space, through some 'adjacent' space. Then I saw/felt "infinity". There was no time, and I saw a hundu-esque god/goddess with infinite arms. I had no interest in eastern religion prior. Not disinterested either. I just didn't think about it, the way I don't think about golf.

It was a neat thing to experience.

Small doses. Never enough to disassociate. Only lots of LSD and 4-HO-DET ever did that to me.

The most striking memory with DMT was at night seeing a moonlight cloud full of skulls staring back down at me. I frequently saw skulls in any texture.

It was very long ago. Unfortunately the dealer was raided.

It left a noticable residue in the simplistic vape we had and a few subsequent uses still carried traces of it.

Haven’t tried it, but I’ve been told by decades of research that it is present in many common plants, mostly in low but in certain cases substantial quantities, and merely needs to be extracted and purified via recrystallization.