I don't know much about webp other than you get about 50% savings in compression vs png/jpeg, but it does have some hard limits on sizes of images. It doesn't do well with webtoon reading formats (long strip format).

Otherwise, I love webp and use it for all my comics/manga.

It was mostly about compatibility but looks like photoshop supports it now so I guess I can now officially say I don't really care one way or the other.