There’s Hank and John Green’s https://good.store e-commerce website that sells socks, coffee, and soap and donates 100% of the profit to charity.

It’s a borderline example since they largely sell to their fans, but the products have broad appeal and are not branded with their names like most YouTuber products.

They are aiming for the “Newman’s Own” model of creating good products and then donating 100% of profit to charity.