Some sites have a message like "hey, we can't serve you ads, you must be using an ad blocker, stop that and absorb the advertising as is your duty because we need the money". But maybe that's just desperation and they aren't losing much to ad blockers anyway.
Many people believe that the loss is great, especially web site owners, which would certainly explain such messages. But lived experience shows at least me that most people don’t even know what an ad blocker is.