Nothing prevents you from running games under emulation on MacOS.

Apple and Wine provide the tools, and apps like Whisky make them easy to use.

> Essentially, this app combines multiple translation layers into a single translation tool. It uses Wine, a translation layer that allows Windows apps and games to run on POSIX-based operating systems, like macOS and Linux. It also uses Rosetta and the Game Porting Toolkit, which are two official Apple tools that allow x86 programs to run on Apple Silicon and serve as a framework for porting Windows games to macOS, respectively.

Normally, this sort of process would require users to manually port games to Mac. But by combining Wine, Rosetta, and the Game Porting Toolkit, this can all happen automatically.

https://www.xda-developers.com/hands-on-whisky-macos-gaming/

However, as aleays, running games under emulation has a performance cost.