You really shouldn't generalise.
I've been running distance most my life. I stopped when my wife had our first kid to concentrate on working hard and give her as much time off from the kid as I could, then after 6 years I had enough and started running. Two years ago, I hadn't been losing any weight, and I was put on these drugs to help me.
I lost more weight.
I run, walk, and move more than you imagine. It didn't work, but these drugs worked.
Not everything is black and white or fits into your preconceived notions.