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connicpu10/11/20241 replyview on HN

I'm curious what about injectables makes them specifically problematic for long term use? Diabetics already have to inject insulin for the rest of their lives, and an injectable version of the same drug usually has fewer side effects since it doesn't have to pass through your gut metabolism. I may be biased, I have no fear of needles and have injected myself with sex hormones every week for nearly 7 years, so adding an autoinjector doesn't seem like that big a deal to me.


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cyberax10/11/2024

They are more expensive. Autoinjectors are way more complicated than a pill bottle. You also can't freeze them, but they should be kept in a fridge.

Manufacturing standards also have to be way higher. I have no problem trusting Novo Nordisk to manufacture injectors safely, but I won't trust a random manufacturer from India or China.

The risk of accidental infection from injection also is not neglibible.

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