> Serious question but has there ever been a case of humans benefitting from increasing a hormone like this?

By itself this might be an ok question, but in context it's rather useless....

Diet and obesity changes by both lowering and increasing different hormone outputs in your body. You're balancing the question of "how is this hormone" versus "How bad is obesity on the body". Well, the answer is in, obesity is extremely unhealthy on the body in both the short and long term.

Drug overdoses cause somewhere around 100k deaths per year in the US. Obesity complications related deaths are in the 250-300k deaths per year.

You can be skeptical as you want, but behind smoking, obesity is the worst epidemic in the US.