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spondylosaurus10/11/20241 replyview on HN

"You'll regress if you stop taking the drugs" may be true, but it seems like a double standard to frame it as a knock against weight loss drugs when this also describes countless other interventions for chronic issues...

Your lupus will flare up again if you stop taking Plaquenil! Your eyesight will be bad again when you take off your glasses!


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tjohns10/11/2024

I actually agree entirely.

I'm just being objective in stating that the evidence suggests that these drugs need to be taken long term to have lasting effects. Not everyone realizes this.

But I think that's okay if it can get people back down to a healthy weight. The health impact from being overweight is serious, and we know that lifestyle intervention has a stunningly abysmal success rate.

Anything we can do to reverse the obesity epidemic is a good thing.

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