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formerly_proven10/11/20248 repliesview on HN

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foobarchu10/11/2024

This thread has multiple people relating their personal stories of using ozempic to start building those healthy habits. Also, it doesn't just magically get rid of fat so you can eat more, its supposed to make you feel full longer (as I understand it, someone feel free to correct me on that).

Plus, even if it did magically get rid of fat temporarily, I'd rather encourage people to do something rather than simply shaming them for giving into a very human addiction.

Your biggest concern around glp-1 drugs shouldn't be the overweight people successfully slimming down, it should be people who are already a healthy enough weight who think they need to be even skinnier (something I've encountered plenty of).

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cthalupa10/12/2024

Yes, it is within the realm of human power for every individual to not be obese.

But the fact of the matter is... a huge chunk of people don't succeed. 42% of American adults are obese. "Eat better and exercise" has not resolved the issue.

I spent a good chunk of my adult life eating well, doing cardio, lifting weights and loving it. Then I got busy with life and stopped. And it has been incredibly difficult to get back to that and gets harder as I get older. I don't think I'm some paragon of willpower - if so, I wouldn't have fallen off the wagon. But I think it would also be silly to think that if someone who has a proven track record of maintaining that for years can struggle with maintaining it for a lifetime, there's probably a lot of people who have never even had that much success who are going to have even worse of a time.

Are we going to moralize over bp meds and statins too? If people can't adapt, fuck 'em, let 'em die young?

tomrod10/11/2024

We don't get pissed that elephants don't climb trees. What value is it to characterize people's obesity entirely as slovenness and gluttony? While there are certainly some slobs and glutton, dismissive judgmentality of everyone doesn't make sense.

For this reason, I believe your comment is lacking in empathy for people who may struggle differently than you, yet struggle all the same.

JamesBarney10/11/2024

Sure of the almost 8 billion people in the world there are plenty who have successfully lost and kept off weight.

But if you want to see if there is a reproduceable lifestyle intervention that treats obesity successfully in the long term you can look here. After a few hours of searching you will probably find the same thing I and almost all obesity researchers have concluded. There isn't one.

https://pubmed.ncbi.nlm.nih.gov/

BurningFrog10/12/2024

This is such a judgmental take.

There are two ways to lower weight. Eat less, and Ozempic. I don't think it's any of my business which one people pick. The important thing is that they become healthy.

I've realized people are very different. Some can just decide to eat less by applying a little willpower. For others, that's incredibly hard. If you're in group 1, it's easy to think everyone is and be appalled how others can't even put in that little bit of effort.

phil2110/12/2024

Can you provide evidence that a statistically significant portion of the population have managed to maintain weight loss in the manner you describe?

The evidence I see does not support your claim. Obesity rates have only gone up during my lifetime and the folks I know in the medical field have consistently mentioned how diet and exercise simply does not have any sort of patient compliance. The folks who successfully do it are outliers.

I will go for the harm reduction principle on this one. The molecules themselves are trivially mass produced for less than $10 a dose and are already being sourced for that cost by folks who are willing to take a bit more risk to do so. Cost seems to be about the only major side effect so far.

amanaplanacanal10/12/2024

You are recommending a course of action that just doesn't work for the great majority of people. Why?

skywhopper10/12/2024

You clearly know nothing about these drugs or about the causes of obesity. This is a disgusting and hateful comment.