Having experienced this exact dosage, I can attest it is more of just raw dragon-chasing juxtaposed with an insane tolerance curve.
The euphoria caused by MDMA combined with literally any other drug (MDMA is like ketchup, can be combined with anything) synergizes and can quickly escalate to rampant re-dosing that _exponentially_ increases tolerance, all while preventing the receptor to re-regulate.
The "sads" following MDMA binges are so ironically over-bearing to a point of near artificial-ness and it is nearly obviously attributable to the chemical.
MDPM/6-APB are interesting as they are euphoric and serotonic but with less manic depressive the next circadian cycle.