It's all guesswork until we start measuring the impact of interruptions in open plan offices vs. homes (which is going to vary with families).
"Interruption" is only one side of the coin, there's usually a reason why somebody is interrupting you and not being able to interrupt you (=not get an important information) will often cost a lot for their productivity.
I think it heavily depends on the person and type of work. I'm SWE and for most daily work I don't mind getting interrupted - I'm able to get back to work without a problem. It's only if I work on an extra difficult problem which requires very deep focus, I go somewhere quiet, but that's less than once a week.
Don’t forget the biggest interruption of all … the commute, sometimes 1-2 hours or more per day, just to get to the office and take advantage of the “benefits”.