You can make short cycles once or twice a year relatively safe for some steroids. Keep close track of your liver enzymes and blood pressure, discontinue if those look bad, otherwise stay on for 4-6 weeks, take half a year off, repeat. Got exposed to people doing that when I was in the gym frequently, still keep up with some now, all their levels look fine.

But even with significant additional intervention, when you move beyond that to the "blast and cruise" setup, those interventions are just mitigating factors, not truly preventative.

I get what you're saying, I've never touched any of them myself, because the juice wasn't worth the squeeze (hah), but if they did have very good safety profiles, I would have zero problem with anyone taking them and would think it would be silly if anyone did.