> Some emulators have tools built in for that, like Dolphin for example.

This was an advertised feature of some DS flashcarts back in the day, too. I can't remember if it was the R4, the DSTwo, or what...but I recall an example video for their "Make your own cheats!" feature, which involved playing something like Super Mario Bros, turning on the "Cheats Finder" feature, then grabbing a coin, and maybe doing it a few times. The manager would then figure out the value that's changing in memory (presumably the sector that stores your coin amount), create the "cheat", and then you would enable it and watch your coin value go up.