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culi11/08/20243 repliesview on HN

> Methamphetamine is a whole other level of stimulant.

The extra methyl group that differentiates it from regular amphetamine salts mainly serves the purpose of crossing the blood-brain barrier quicker. However, during this process it loses that extra methyl group. So whether you're taking meth or adderal, the chemical that actually reaches your brain is ultimately the same

In fact, methamphetamine is available as a prescription ADHD medicine under the brand name "Desoxyn"


Replies

jart11/08/2024

I thought that (1) meth (e.g. methylphenidate a.k.a. ritalin) blocks reuptake of dopamine, and (2) amphetamine (e.g. dextroamphetamine) stimulates production of dopamine, and (3) methamphetamine (a.k.a. desoxyn) does both. Is that understanding accurate?

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InDubioProRubio11/08/2024

And you get a erdös number for taking them : https://en.wikipedia.org/wiki/Paul_Erd%C5%91s#Personality

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EdwardDiego11/08/2024

Yeah, precisely, that methyl group is why methamphetamine is super popular, it makes a whole lot of difference in the felt effect.