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robinduckett11/08/20243 repliesview on HN

They have oxymetazoline but I think the problem with this class of decongestants is that it is ineffective and dependency is basically guaranteed if used for more than a couple of days


Replies

deng11/08/2024

Oxymetazoline is different from Xylometazoline, although it was derived from it. Xylometazoline is pretty harmless for adults when not used over extended periods (it is advised to not use it longer than 6 days, but that will cover your typical cold). It is true that if you take it regularly over extended periods, you will have a rebound effect and your nose will get congested when not taking it, so in that way, you develop a "physical dependency", but that's obviously much more harmless than other medication dependencies. Getting off a Xylometazoline dependence means that you'll have to deal with a congested nose for a few weeks...

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sph11/08/2024

Worse, the symptoms gets worse after you stop using it, see rhinitis medicamentosa.

Many people have used decongestants so much they cannot quit them or will have to suffer weeks of nasal congestion. I risked going through that; later I swore I will never touch one ever again.

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dreamcompiler11/08/2024

Oxymetazoline is an extremely effective nasal decongestant. It works almost instantly and it lasts 24 hours.

It also creates dependency. A drug that is ineffective cannot cause dependency.

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