Everything that works on Linux will generally work on Qubes, apart from the GPU-heavy applications [0], which will be addressed in the future [1]. Copying and pasting works fine [2]. OK, music production may not be possible at the moment [3].

[0] https://www.qubes-os.org/faq/#can-i-run-applications-like-ga...

[1] https://github.com/QubesOS/qubes-issues/issues/8552

[2] https://www.qubes-os.org/doc/how-to-copy-and-paste-text/

[3] https://forum.qubes-os.org/t/question-quality-of-external-us...