I would guess that it would still be possible to send things beyond earth's orbit with only a low probability of collision with debris but perhaps I'm wrong.
Every launch failure will result in more debris and even lower probability of a successful future launch.
"Low" is tough to say until someone does some proper sort of 'true mapping' of space debris in the range somehow. Protection would require a lot of complexity and cost due to the need for shielding and the delta-v to move it up there.