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cyberaxlast Thursday at 5:48 AM2 repliesview on HN

> For the people who lift weights while on this/these drugs, how much lean muscle do they lose?

I was 92kg when I started on liraglutide (I was doing GLP-1 agonists before it was cool!) and 67% of muscle mass (61kg). I'm now at 69kg and 82% of muscle mass (56kg). I'm doing weight and resistance training twice a week, in addition to aerobic training.

One nice thing, while muscles don't become more massive, they for sure become more pronounced and visible with weight loss.


Replies

metafunctorlast Thursday at 10:49 AM

Those muscle mass percentages cannot be right. How were they measured?

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scotty79last Thursday at 10:03 AM

I'd bet you are stronger now despite slightly lower muscle mass.

Probably the muscle tissue people lose first are crappy cells. Weak, nonfunctional, senescent or even maybe some muscle embedded fat.

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