That's true for an individual, but if you're looking at a population then you're seeing a situation where we have zero other solutions that are actually effective at curbing obesity. The only "natural" way to solve it is probably to overhaul our entire culture, redesign our cities and neighborhoods, et c., and that's not happening.

Skinny people move to the US and get fat. They're not skinnier back in their home country because they've got greater willpower or are harder workers, but because they aren't in the US. If harder work isn't why skinnier countries are skinnier, we shouldn't expect it to help us out of our problem, and indeed, we have nothing else we've studied that is terribly effective over time, and certainly nothing cheap enough to deploy on a large scale.

Again, yes, for an individual your perspective is the only thing one has (well... until these drugs) but looking from a policy level, it's useless.

> The only way to lose weight without damaging oneself is to combine more exercise with less eating, which means becoming comfortable being hungry

No, not really. Yes, this is how you lose weight, but this is not how you have to be to be a healthy weight.

I'm thin, I don't exercise, and I'm not hungry. I feel great.

I can sit around and jerk myself off about discipline, but the truth is I have none. I have done absolutely nothing to be in this position, it's all luck and factors far beyond my comprehension.

if a drug is able to induce that same feeling in others, I say go for it. It sucks that a normal caloric intake translates to pain, hunger, and constant brain noise for a large segment of the population.