Talking to NPCs in games is really just reading dialog written by humans.

If you could actually talk to NPCs as in get their thoughts about the world and ask open ended questions, that’d be very interesting.

If I could talk to something at the level of Neuro-sama (https://www.twitch.tv/vedal987) I'd be very entertained and it's essentially a matter of time. Hell, I'd love to have something like this as an assistant application as well and I'm not a Cortana/Google Assistant/etc user.