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hatefulmoron01/22/20251 replyview on HN

The figure also shows that the non LLM algorithm from 2012 was as capable or more capable than a human: was it as intelligent as a well educated human?

If not, why is the study sufficient evidence for the LLM, but not sufficient evidence for the previous system?

Again, it feels like statistical methods are winning out in general.

> Perhaps it’s better that you ask a statistician you trust

Maybe we can shortcut this conversation by each of us simply consulting O1 :^)


Replies

nopinsight01/22/2025

1) It’s an example of a domain an LLM can do better than humans. A 2012 system was not able to do myriad other things LLMs can do and thus not qualified as general intelligence.

2) As mentioned in the chart label, earlier systems require manual symptom extraction.

3) An important point well articulated by a cancer genomics faculty member at Harvard:

“….Now, back to today: The newest generation of generative deep learning models (genAI) is different.

For cancer data, the reason these models hold so much potential is exactly the reason why they were not preferred in the first place: they make almost no explicit data assumptions.

These models are excellent at learning whatever implicit distribution from the data they are trained on

Such distributions don’t need to be explainable. Nor do they even need to be specified

When presented with tons of data, these models can just learn, internalize & understand…..”

More here: https://x.com/simocristea/status/1881927022852870372?s=61&t=...