alt Hacker NewsThat a UPR inhibitor would inhibit viability of AML cell lines is not exactly a novel scientific hypothesis. They took a previously published inhibitor known to be active in other cell lines and tried it in a new one. It's a cool, undergrad-level experiment. I would be impressed if a sophomore in high school proposed it, but not a sophomore in college.
Replies
Only two years since chatGPT was released and AI at the level of "impressive high school sophomore" is already blasé.
I have a less generous recollection of the wisdom of sophomores.
I’m not familiar with the subject matter, but given your description, I wouldn’t really be impressed by anyone suggesting it. It just sounds like a very plausible “What if” alternative.
On the level of suggesting suitable alternative ingredients in fruit salad.
We should really stop insulting the intelligence of people to sell AI.
I'm sure the scientists involved had a wish list of dozens of drug candidates to repurpose to test based on various hypotheses. Ideas are cheap, time is not.
In this case they actually tested a drug probably because Google is paying for them to test whatever the AI came up with.
Incremental progress is incremental progress.
(to be Shpongled is to be kippered, mashed, smashed, destroyed...completely geschtonkenflopped)
> I would be impressed if a sophomore in high school proposed it
That sounds good enough for a start, considering you can massively parallelize the AI co-scientist workflow, compared to the timescale and physical scale it would take to do the same thing with human high school sophomores.
And every now and then, you get something exciting and really beneficial coming from even inexperienced people, so if you can increase the frequency of that, that sounds good too.