> Regulations around clinical trials represent the floor of what's ethically permissible, not the ceiling.
Disagree. The US FDA especially is overcautious to the point of doing more harm than good - they'd rather ban hundreds of lifesaving drugs than allow one thalidomide to slip through.
Yeah that's not how anything works. Compounds are approved for use or not based on empirical evidence, thus the need for clinical trials. What's your level of exposure to the pharma industry?