Yes. React runtime included. Benchmark and details here: https://nuejs.org/docs/react-button-vs-nue.html
This comparison is disingenuous and off-putting. When I read "a React button" I assume you are talking about `<button>` and the React runtime, not some third party libraries.
As the previous commenter said - you don't need a new runtime instance per button, so the comparison doesn't really work (for the smallest binary size, you could provide a native application doing the bare minimum to display the UI too, if the platform has an OS-provided UI framework).
It's still a neat toolkit, since not every website needs a big framework - but comparing runtime sizes is like choosing C over C++ because a `int main() { printf("Hello World\n"); }` binary is smaller.