logoalt Hacker News

vikramkr04/28/20250 repliesview on HN

looks like it - it's such a minor and brief mention in the paper for the article to focus on it so much lol. They probably should have cited it, looks like they decided it was minor enough (or forgot) that they didn't put it in their software used/citation. Super commonly used though I wouldn't be stunned if most of its uses never got cited- just a quick check if it thinks deleting some section or doing some sort of fusion is gonna cause a problem, or if you've got something without a PDB structure finding a site to mess with that looks like it's not gonna cause any problems. You can't count on it blindly obviously but it's super helpful. Like if it's pretty confident about some section of a protein it hasn't seen before, the weird stuff you're studying might not be folded properly by the model, but if you want to stick a handle onto the protein to grab it with whatever it can let you know where's the least likely to be a waste of time and money to try.