The amyloid hypothesis is absolutely not correct. We know this unequivocally.

Amyloid deposits correlate with Alzheimer’s, but they do not cause the symptoms. We know this because we have drugs which (in some patients, not approved for general use) completely clear out amyloids, but have no affect on symptoms or outcomes. We have other very promising medications that do nothing to amyloids. We also have tons of people who have had brain autopsies for other reasons and found to have very high levels of amyloid deposits, but no symptoms of dementia prior to death.

Alzheimer’s isn’t caused by amyloids.