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aydyn06/04/20251 replyview on HN

You can expect different modes between fasting and caloric restriction. You might even consider one mode "better", but what is missing is any evidence that it leads to difference in outcomes.


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_Algernon_06/04/2025

For a healthy individual it might not make a difference, but increased insulin sensitivity may help in (pre-)diabetics for instance.

>Studies have shown intermittent energy restriction to be efficacious in preventing and managing prediabetes and DM, with remarkable improvements in the metabolic and cardiovascular biomarkers of individuals with DM.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9534344/