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dymk06/17/20251 replyview on HN

I'd call that a case of the drug(s) they were on blocking the effect due to an apparently permanent change to their brain chemistry.


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esseph06/17/2025

Some of them were younger, in their 20s with long lasting depression and no history of medication in the last ~2y.

This wasn't some like, "weekend experience" but more multi-decade "experiments" with some extremely well educated friends, coworkers, etc.

Group size of around 30.