That depends on what kind of filtering is used when upscaling those icons. If you use modern resampling filters, you are more likely to get a subtle "oil painting" or "watercolor"-like effect with some very minor ringing effects next to sharp transitions (the effect of correctly-applied antialiasing, with a tight limit on spatial frequencies) as opposed to any visible blur. These filters may be somewhat compute-intensive when used for upscaling the entire screen - but if you only upscale small raster icons or other raster images, and use native-resolution rendering for everything else, that effect is negligible.