One more data point: at work we use Stripe for most regions [1], but in our largest region (South Africa) we have to use Paystack [2] (a Stripe subsidiary). The API isn't 1:1 compatible and there's no plans to do so in the near future. Having multiple providers is a must for us to consider a solution.
Lago is better in that they have have support for custom payment integrations [3].
[2] https://paystack.com/stripe/south-africa
[3] https://getlago.com/docs/integrations/payments/custom-paymen...
This is really helpful context. Thanks for sharing!