I use the amdgpu driver and my luck has not been as good as yours. Can't sleep my PC without having it wake up to fill my logs with spam [0] and eventually crash.

Then there is the (in)famous AMD reset bug that makes AMD a real headache to use with GPU passthrough. The card can't be properly reset when the VM shuts down so you have to reboot the PC to start the VM a second time. There are workarounds but they only work on some cards & scenarios [1] [2]. This problem goes back to around the 390 series cards so they've had forever to properly implement reset according to the pci spec but haven't. nvidia handles this flawlessly

[0] https://gitlab.freedesktop.org/drm/amd/-/issues/3911

[1] https://github.com/gnif/vendor-reset

[2] https://github.com/inga-lovinde/RadeonResetBugFix