I mean outside of HPC why would you when the browser is the world’s most ubiquitous VM?
A lot of us just don't want to be web developers. I mostly write IEC 61131 code, with sprinkles of BASIC (yuck), C, Perl, and Lisp. I've used JavaScript and quite frankly, you can keep it.
If you want something better than UI designed for toddlers
Offices when the performance matters against shitty web apps.
Because the browser is gross and you can reclaim lot of performance and security when you don't need to use it.