My Linux machine is very modern, but I still need i386 architecture support installed, because Steam requires 32-bit support. And Steam requires 32-bit support so people can play 15-year-old games.
(Admittedly, the 32-bit support Ubuntu ships is less than a full OS and you can't install Ubuntu on a 32-bit machine these days)
Debian is doing basically the same thing Ubuntu is with regards to i386. Packages are still being built for the architecture, but i386 systems aren't supported, and there's no 32-bit kernel package.
e.g. notice that i386 is still listed at the bottom of https://packages.debian.org/trixie/bash
I don't think this is the case anymore, see https://gitlab.winehq.org/wine/wine/-/releases/wine-9.0#wow6... though it's not the default everywhere.
So you have an amd64 CPU and Debian's "i386" packages will keep working on it. As per the release notes:
> The i386 architecture is now only intended to be used on a 64-bit (amd64) CPU.