Some remote MCPs will get locked down to know client endpoints, same as any other HTTP service, so if companies are really concerned about them being AI-use-only and don't mind cutting off some AI use to preserve that exclusivity, they’ll lock it down to the big known hosted AI frontends (assuming those end up supporting MCP; the only one I know of that does currently is ChatGPT Deep Research, and only for very limited shapes of servers.)

OTOH, that only effects those services, it won't stop people from leveraging MCP as, say, a generic local plugin model for non-AI apps.