I am a strict atheist, but we cannot know. I faithfully believe that, finding no proof whatsoever, and the existence of a metaphysical/spiritual world coexisting with ours incredibly unlikely without some evidence, there is no god.
But, just like my faith in the supremacy of the speed of light, that's just my opinion, man... based on the combined knowledge of the human race and thousands or millions of experiments.
That's pretty much the definition of "agnostic". The gnostics literally claim to know and the agnostics say "Nope. Do not. In fact, we can't."
Agnostics can play the odds and base their actions on what they find more plausible precisely _because_ they haven't pre-committed to a specific answer.