> without performance concerns?

WASM isn't going to magically make the DOM go faster. DOM will still be just as slow as it is with Javascript driving it.

WASM is great for heavy-lifting, like implementing FFMPEG in the browser. DOM is still going to be something people (questionably) complain about even if WASM had direct access to it. And WASM isn't only used in the browser, it's also running back-end workloads too where there is no DOM, so a lot of use cases for WASM are already not using DOM at all.