Surprisingly, no. Most sites do a good job of finding and banning bots. It's also fairly easy to spot a bot. They will make odd sized bets at times. You check to see if that betting line is taken in a solver.
Then you have to worry about the site itself being shady. Live poker is really the only path. Plus it's so much more fun.
Sites have very a strong incentive to make you believe this. Otherwise no human would join anymore.