Autofill doesn't always work for every site. So, now you're having to store in your mind where it works and where it doesn't. By disabling it, it forces you to go the extra step (command-shift-L) every time.
Autofill and the hotkey use the same mechanism, and neither is going to work on a phishing site.
Autofill and the hotkey use the same mechanism, and neither is going to work on a phishing site.