I'm sure there is some, but it's standard practice to keep at database of all your hands. I've sanity checked the winning regs (at my stakes) and they all make mistakes. I think it helps that in the US all the sites are geography based. It makes it harder and less financially viable to run a bot ring.
I don't know what a reg is but I would assume the first thing you do after you get your bot working is to add some imperfect play so that you don't get banned by the most trivial heuristics.