It's not exactly a big problem, but my company makes a three-axis desktop CNC machine powered by an ATMega328P that is dependent on having a Windows PC connected to it in order to run the proprietary software. Uno Q has me thinking we can eliminate the PC along with our custom PCB, making a more compact and convenient stand-alone system that would also come with a lower price tag. I may order a few to experiment with this idea, but again, it's not a huge problem and something only specific customers would care about.
I'm curious what the Maker community comes up with, provided it sticks around and remains supported, unlike the Edison.
> Uno Q has me thinking we can eliminate the PC along with our custom PCB
If you know how to eliminate the PC, why not replace it already with a Pi?
Take a look at the MKS-DLC32 board. It's a (documented, but poorly!) ESP32-based 3-axis 3D printer controller board. It runs grbl on one core so it can understand g-code, and it has a local UI with web and BLE connectivity on another core. The source code is on github, although it takes a bit of digging to find it (that poorly documented part!).
I don't know how complex your Windows code is, but it's an interesting architecture to study. I bought one of the boards (they're all over Amazon) since it had everything I needed for a motion-control project, but I ended up with a simpler solution.