The wrongs of religion throughout history are typically exaggerated in modern times and the Spanish Inquisition is one of the best examples of this. It lasted more than 350 years and during this 350 years a very high-end estimate of executions is 5000. So the death toll from it ranges probably from one person every ~3 months to one person every month. [1]

So for some comparison, 2-5x more people die in the US of lightning strikes each year than died during the Spanish Inquisition per year. Obviously any death is undesirable, but describing it as a horrific mass-murder is hyperbolic. It was rather more a mass public shaming campaign like the Chinese Struggle Sessions, but many orders of magnitude smaller in scale.

For that matter even the Mayans were likely sacrificing people on a far larger scale. We lack exact numbers but know that they did group sacrifice, often of children, and that this was regularly done when building new structures, or for hopes of a good crop season and the like. And I think the thing that makes human sacrifice particularly primitive in its nature is that obviously doesn't work. Whether you killed a dozen kids or not has no bearings on how your crops grow. And so they would have to, over centuries, continue to reject the evidence before their eyes.

[1] - https://en.wikipedia.org/wiki/Spanish_Inquisition#Death_toll...