Possibly, although I think the Aztecs specifically was likely doomed from the start because they were a very young society and a brutal military conqueror and everybody they dealt with hated them, but you never can know. However the Aztecs were far from the only significant America Native society or civilization. There were many others, especially to the South, that we know were far more stable societies and governments producing more advanced goods and had high levels of trade amongst each other. South America was essentially in their own bronze age at the time and their gold and precious metal work was beyond what anybody in Europe was able to replicate at the time.