Hmm. IME VB6 is actually a particular pain point, because MDAC (a hodgepodge of Microsoft database-access thingies) does not install even on Windows 10, and a line-of-business VB6 app is very likely to need that. And of course you can’t run apps from the 1980s on Windows 11 natively, because it can no longer run 16-bit apps, whether DOS or Windows ones. (All 32-bit Windows apps are definitionally not from the 1980s, seeing as the Tom Miller’s sailboat trip that gave us Win32 only happened in 1990. And it’s not the absence of V86 mode that’s the problem—Windows NT for Alpha could run DOS apps, using a fatter NTVDM with an included emulator. It’s purely Microsoft’s lack of desire to continue supporting that use case.)
Wait, what's the story of the sailboat trip? My searches are coming up empty, but it sounds like a great story.