>for example in Dota2 it doesen't matter how fast you click an entity, because the turnrate of your character is limited, so a person clicking reasonably fast and a bot clicking in 0.01ms both arrive there at the same time. Precision also doesn't matter, because a player can click the icon of the enemy instead of trying to match the pixels on screen.

Even with turnrate, reaction time is very relevant. Reaction time allows you to silence enemies midcast, or to pop a shield, or a BKB, or some other instant measure. Turnrate doesn't mean reaction time doesn't matter, it means the direction you are facing matters.

As for precision, yes it does matter, ask any Phoenix player who gets hexed mid-flight.

People cheat in Dota in these very terms, it's absurd to argue it doesn't matter.