In the US, you don’t need a neutral for a 240V 50A circuit on a residential single-phase service, there are two line conductors (120V to ground) both connected to a 2-pole single-phase breaker, line-to-line between the two is 240V.
You would need a neutral if it was a 208/120V three-phase service.
Neutrals and grounds are sized per the NEC, neutrals are the same size as the line conductors and equipment grounds are sized off of a table.
#6 conductors and #10 ground is what the NEC calls for.
I just haven't seen server rooms that don't demand a doubly sized neutral when one is required.
I live the NYC 208V life doing mostly resi, though.
Quick search of the spec for that is 6 power supplies, 2 of which are redundant. Looks to use a neutral to me. Says it uses C19/C20 connectors
edit: wait most ranges use 14-50R outlets and need a neutral ran. I am calling your statement into question. Surely harmonics and 120V internal draws cause non-zero neutral current. And I'm sure GPUs have harmonics being semiconductor flavored.