Well, Typed Clojure is a thing!

But the real strength of Lisp is in the macros, the metaprogramming system. And I suspect that typing most macros properly would be a bit less trivial than even typing of complex generic types, like lenses. Not typing a macro, and only typechecking the macroexpansion would formally work, but, usability-wise, could be on par with C++ template error reporting.

That means little to a programmer unless they really want to spend thousands of hours building a type checker before starting a project.