To me, 100-500x higher death rates are simply not a detail that I can get past. Since we are basically of the same genetic makeup (which is also the cornerstone of you argument) that simply seems incompatible with a better life. It's possible I am lacking vision for how it all gels into the good existence you think it does.
What I think makes this idea interesting: We are not as fantastically happy today as we should be, if progress on the tangibles translated into happiness. So there's definitely something that is off and I can totally see what you are describing being part of it.