One of the few problem of nuclear is summer time water use. Combining solar with nuclear would be the best option in my opinion.
Historically the biggest impediment to nuclear power has been incompetent construction management and project management. Incompetent is a strong word for it but nuclear power plants are the largest capital equipment purchases on the planet. Even modern so-called modular designs can't save poor project management, and learn as you go engineering.
That so mundane and should be easy to fix, right? That's why I bring up scale. Nobody has experience running projects that big. Some things are just too big to manage.
Nuclear plants, like most large thermal plants, are almost always located near large bodies of water and return that water downstream so it doesn't really matter?