I've been using an eInk screen for over 12 years - it is refreshed multiple times per day.
It is as crisp and clear as the day I got it.
Admittedly, I'm not trying to run video on it constantly and it doesn't get hot. But eInk seems remarkably durable.
That's probably, what, 200,000 refreshes?
From what I gather, at book-reading speeds, newer e-ink displays may never wear out in a human lifetime.
But at usable computer display speeds I rather suspect many of these panels have a lifetime one might measure in months.